Friday, 20 August 2010
Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX.
Penile numbness is a rare complication of permanent prostate brachytherapy, and optimal clinical management remains unclear. We present such a case and discuss pathophysiology and clinical management strategies.
A 68-year-old male presented with a serum prostate-specific antigen level of 6.9 ng/mL, Gleason score of 7 (3+4), and clinical T1c adenocarcinoma of the prostate. After a permanent prostate brachytherapy implant with (125)I monotherapy to a dose of 145Gy, the patient developed complete penile numbness postoperatively on the third day.
The patient experienced complete restoration of penile sensation and function by postoperative day 9 with conservative management.
Subacute penile shaft numbness after brachytherapy is rare and is caused by dorsal penile nerve compression. Over the course of a week, the restoration of penile sensation is likely to occur with conservative management.
Written by:
Sharp HJ, Swanson DA, Patel H, Gorbatiy V, Frenzel JC, Frank SJ. Are you the author?
Reference: Brachytherapy. 2010 Aug 2. Epub ahead of print.
doi: 10.1016/j.brachy.2010.02.197
PubMed Abstract
PMID: 20685173
UroToday.com Prostate Cancer Section
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2 comments:
I am having this condition as well. Cannot find anything but this one case study. My symptoms are at day 35. Slow, mild improvement noted. Numbness in head of penis and mild pain when urinating. On Flomax, did have brachytherapy. Any help on causes or treatments is appreciated!
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